Claims for Patent: 4,584,194

Summary for Patent: 4,584,194

Title:	Inactivated rabies vaccine for veterinary use
Abstract:	The preparation of a vaccine for immunization of canine and feline animals from inactivated HCP-SAD strain of rabies virus is disclosed.
Inventor(s):	Bass; Edmund P. (Lincoln, NE), Sharpee; Richard L. (Lincoln, NE)
Assignee:	Norden Laboratories, Inc. (Lincoln, NE)
Application Number:	06/720,849
Patent Claims:	1. A method of vaccinating canine animals comprising administering parenterally to said animals an inactivated rabies vaccine capable of inducing immunity in canine animals without serious side effects, the vaccine comprising a vaccinal amount of inactivated HCP-SAD strain of rabies virus which has been adapted, before inactivation, to grow in swine testicle cell culture by at least one passage therein, an adjuvant and a carrier therefor. 2. The method of claim 1 wherein the vaccine is administered by intramuscular injection. 3. The method of claim 1 wherein, in the vaccine, the rabies virus has been passaged from 1 to about 25 times in a swine testicle cell culture. 4. The method of claim 3 wherein the vaccine is administered by intramuscular injection. 5. The method of claim 1 wherein, in the vaccine, the virus has been passaged from about 6 to about 12 times in a swine testicle cell culture. 6. The method of claim 5 wherein the vaccine is administered by intramuscular injection. 7. The method of claim 5 wherein the swine testicle cell culture is the NL-ST-1 swine testicle cell line. 8. The method of claim 7 wherein the vaccine is administered by intramuscular injection.

Details for Patent 4,584,194

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bavarian Nordic A/s	RABAVERT	rabies vaccine	For Injection	103334	10/20/1997		2003-04-22
Sanofi Pasteur Sa	IMOVAX RABIES	rabies vaccine	For Injection	103931	02/04/2000		2003-04-22