➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Merck
Baxter
Moodys
Colorcon
McKinsey

Last Updated: September 18, 2021

DrugPatentWatch Database Preview

Claims for Patent: 4,507,389

➤ Get the DrugPatentWatch Daily Briefing

« Back to Dashboard

Summary for Patent: 4,507,389
Title: Determination of collagenase by reacting with peptide substrates
Abstract:Synthetic peptide substrates having high activity for the enzyme collagenase. These substrates have the following amino acid sequences: and wherein R.sub.1 =H or N-protecting group, and R.sub.2 =terminal amide, carboxyl or ester group. These peptide substrates are useful for determining collagenase activity.
Inventor(s): Weingarten; Harold I. (University City, MO)
Assignee: Monsanto Company (St. Louis, MO)
Application Number:06/590,395
Patent Claims:1. A method for the determination of collagenase in a biological sample comprising reacting an aqueous solution of said sample with a peptide substrate selected from the group consisting of

and

wherein

R.sub.1 =H or N-protecting group, and

R.sub.2 =terminal amide, carboxyl or ester group, and measuring the time of cleavage product formation.

2. The method of claim 1 in which the peptide has the structure

3. The method of claim 1 in which the peptide has the structure

4. The method of claim 1 in which the peptide has the structure

Details for Patent 4,507,389

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Free Forever Trial Monsanto Company (St. Louis, MO) 2002-12-16 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Medtronic
Moodys
Johnson and Johnson
Dow
Harvard Business School
Merck

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.