Claims for Patent: 4,499,901
✉ Email this page to a colleague
Summary for Patent: 4,499,901
Title: | Retreated sensing electrode |
Abstract: | An improved sensing electrode assembly for testing for a constituent in blood is provided. An electrode assembly exhibits a decreased time to reach stable operation by virtue of having the assembly pretreated by applying thereto a liquid containing blood derived albumin. |
Inventor(s): | Chang; Joseph J. (Tampa, FL), Ramsey, III; Maynard (Tampa, FL) |
Assignee: | Critikon, Inc. (Tampa, FL) |
Application Number: | 06/509,500 |
Patent Claims: | 1. In an electrode assembly for insertion into a living animal to continuously monitor blood gas concentration, which assembly includes an electrode and a hydrophilic polymer
membrane covering said electrode, wherein said membrane is hydrophilic substantially throughout its thickness, the improvement which comprises:
said covering membrane being pretreated by having applied thereto a liquid solution comprising blood derived albumin, said pretreated membrane than being sterilized; and said electrode assembly exhibiting a lower T.sub.S than an assembly having an untreated membrane. 2. The electrode assembly of claim 1 wherein the T.sub.S is less than six hours. 3. The electrode assembly of claim 1 wherein said liquid solution is an aqueous solution. 4. The electrode assembly of claim 1 wherein said liquid solution is a solution of essembly pure blood derived albumin. 5. The electrode assembly of claim 4 wherein said blood derived albumin is human blood derived albumin. 6. The electrode assembly of claim 1 wherein said liguid solution is a solution of blood derived proteins. 7. The electrode assembly of claim 6 wherein said blood derived proteins are human blood derived proteins. 8. The electrode assembly of claim 1 wherein said liquid solution is blood serum. 9. The electrode assembly of claim 8 wherein said blood serum is human blood serum. 10. A method for decreasing the T.sub.S of an electrode assembly for insertion in a living animal to continuously monitor blood gas concentration, which assembly includes an electrode and a hydrophilic polymer membrane covering said electrode, wherein said membrane is hydrophilic substantially throughout its thickness, comprising the steps: pretreating said electrode by applying to said membrane a liquid solution comprising blood derived albumin and then sterilizing said electrode, whereby the T.sub.S of said electrode assembly is substantially lower than an assembly having an untreated membrane. 11. The method of claim 10 wherein said liquid is applied by immersing said electrode in said liquid for at least 10 minutes. 12. The method of claim 11 wherein said electrode is immersed in said liquid for at least one hour. 13. The method of claim 10 wherein said electrode is dried after said solution is applied. 14. The method of claim 13 wherein said electrode is sterilized after it is dried. 15. The method of claim 13 wherein silicone is applied to said electrode prior to drying. |
Details for Patent 4,499,901
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Grifols Therapeutics Llc | ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5 | albumin (human) | For Injection | 101138 | 10/21/1942 | ⤷ Try a Trial | 2040-01-28 |
Baxalta Us Inc. | BUMINATE, FLEXBUMIN | albumin (human) | Injection | 101452 | 03/03/1954 | ⤷ Try a Trial | 2040-01-28 |
Csl Behring Ag | ALBURX | albumin (human) | Injection | 102366 | 07/23/1976 | ⤷ Try a Trial | 2040-01-28 |
Grifols Biologicals Llc | ALBUTEIN | albumin (human) | Injection | 102478 | 08/15/1978 | ⤷ Try a Trial | 2040-01-28 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
Make Better Decisions: Try a trial or see plans & pricing
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.