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Last Updated: March 28, 2024

Claims for Patent: 4,466,919


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Summary for Patent: 4,466,919
Title: Peptide substrates for mammalian collagenase
Abstract:The disclosure relates to novel synthetic peptide substrates having high activity for the enzyme collagenase. These substrates have the following amino acid sequences: and wherein R.sub.1 =H or N-protecting group, and R.sub.2 =terminal amide, carboxyl or ester group.
Inventor(s): Weingarten; Harold I. (University City, MO)
Assignee: Monsanto Company (St. Louis, MO)
Application Number:06/450,318
Patent Claims:1. A peptide material having activity as a substrate for collagenase selected from the group consisting of

and

wherein

R.sub.1 =H or N-protecting group, and

R.sub.2 =terminal amide, carboxyl or ester group.

2. The peptide of claim 1 having the structure

3. The peptide of claim 1 having the structure

4. The peptide of claim 1 having the structure

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