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Last Updated: September 18, 2021

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Claims for Patent: 4,456,544

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Summary for Patent: 4,456,544
Title: Enzyme-containing detergent composition for presterilization treatment of medical instruments and equipment
Abstract:An enzyme-containing detergent composition for a presterilization treatment of medical instruments and equipment, consisting of the following components, percent by weight: anionic surfactants: 4.0-6.0 sodium phosphate: 30.0-35.0 sodium silicate: 20.0-25.0 sodium carbonate: 19.0-22.0 soap comprising sodium salts of fatty acids: 2.0-4.0 enzymatic preparation: 0.5-2.0 sodium sulphate: the balance, the enzymatic preparation having the following composition, percent by weight: alkaline protease: 30-60 neutral protease: 27-45 elastase: 0.01-5.00 collagenase: 0.001-4.00 leucinaminopeptidase: 0.0001-0.011 carboxypeptidase: 0.04-0.15 fibrinolytic enzyme: 0.002-1.500 lipase: 0.5-2.0 amylase: the balance.
Inventor(s): Lupova; Ljudmila M. (Moscow, SU), Fedorova; Lidia G. (Moscow, SU), Grebeshova; Renata N. (Moscow, SU), Aleshina; Zinaida P. (Moscow, SU), Anton; Alexandr G. (Moscow, SU), Belinsky; Alexandr L. (Moscow, SU), Alexeeva; Margarita I. (Moscow, SU)
Assignee: Vsesojuzny Nauchno-Issledovatelsky Biotecknichesky Institut (Moscow, SU)
Application Number:06/520,813
Patent Claims:1. An enzyme-containing detergent composition for presterilization treatment of medical instruments and equipment consisting of the following components, percent by weight:

anionic surfactants: 4.0-6.0

sodium phosphate: 30.0-35.0

sodium silicate: 20.0-25.0

sodium carbonate: 19.0-22.0

soap comprising sodium salts of fatty acids: 2.0-4.0

enzymatic preparation: 0.5-2.0

sodium sulphate: the balance,

the enzymatic preparation having the following composition, percent by weight:

alkaline protease: 30-60

neutral protease: 27-45

elastase: 0.01-5.00

collagenase: 0.001-4.00

leucinaminopeptidase: 0.0001-0.011

carboxypeptidase: 0.04-0.15

fibrinolytic enzyme: 0.002-1,500

lipase: 0.5-2.0

amylase: the balance.

2. An enzyme-containing detergent composition as claimed in claim 1, wherein non-ionic surfactants are additionally present in an amount of 1-2% by weight of the anionic surfactants.

3. An enzyme-containing detergent composition as claimed in claim 2, wherein as said non-ionic surfactants use is made of

a monoalkyl ester of polyethyleneglycol based on primary aliphatic alcohols;

a polyoxyethyleneglycol ester of monoethanolamides of synthetic aliphatic acids.

Details for Patent 4,456,544

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Free Forever Trial Vsesojuzny Nauchno-Issledovatelsky Biotecknichesky Institut (Moscow, SU) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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