Claims for Patent: 10,513,696

Summary for Patent: 10,513,696

Title:	Lucilia sericata collagenase
Abstract:	One complementary DNA (cDNA) encodes a collagenase enzyme of Lucilia sericata that includes an identified sequence. Optionally, the cDNA is applied to wound healing.
Inventor(s):	Alipour; Hamzeh (Bushehr, IR), Raz; Abbasali (Tehran, IR), Dinparast Djadid; Navid (Tehran, IR), Zakeri; Sedigheh (Tehran, IR)
Assignee:
Application Number:	15/410,697
Patent Claims:	1. A complementary DNA (cDNA), wherein the cDNA comprises SEQ ID NO: 1 and encodes a collagenase enzyme of Lucilia sericata. 2. The cDNA according to claim 1, wherein the cDNA encodes a collagenase enzyme of Lucilia sericata with a molecular weight of 45.1 kilodaltons (kDa). 3. The cDNA according to claim 1, wherein the cDNA is identified by a method comprising: extracting RNA from salivary glands of Lucilia sericata; synthesizing the cDNA from extracted RNA; identifying a middle part of the cDNA sequence of Lucilia sericata collagenase; identifying a 3' end of the cDNA sequence of Lucilia sericata collagenase through a rapid amplification of cDNA ends technique (RACE); identifying a 5' end of the cDNA sequence of Lucilia sericata collagenase gene through a rapid amplification of genomic ends technique (RAGE); and identifying a full-length cDNA sequence of Lucilia sericata collagenase, the full-length cDNA sequence being as set forth in SEQ ID NO: 1.

Details for Patent 10,513,696

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965		2036-05-24