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Last Updated: April 24, 2024

Claims for Patent: 10,232,004


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Summary for Patent: 10,232,004
Title:Pharmaceutical composition based on Centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers
Abstract: A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers, including as active ingredients, centella asiatica and sodium acexamate in amounts producing a reciprocal synergistic effect when mixed with at least one adjuvant selected from a healing agent, an antibiotic agent and/or combinations thereof is described.
Inventor(s): Montanez-Soto; Flor Lucia (Veracruz, MX)
Assignee:
Application Number:14/784,085
Patent Claims:1. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers, comprising about 10% to 18% by weight of centella asiatica, about 67% to 75% by weight of sodium acexamate, and about 10% to 18% by weight of an antibiotic agent.

2. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers according to claim 1, further comprising about 60 U of collagenase.

3. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers according to claim 2, wherein the collagenase is clostridiopeptidase A.

4. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers according to claim 1, wherein the antibiotic agent is selected from chloramphenicol, sulfathiazole powder, and ciprofloxacin.

5. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiaticaL.) for the treatment of lower limb ulcers according to claim 2, wherein the composition comprises a bout 14% by weight of centella asiatica; about 71% by weight of sodium acexamate; about 14% by weight of chloramphenicol; and about 60 U of collagenase.

6. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiaticaL.) for the treatment of lower limb ulcers according to claim 1 wherein the composition comprises about 14% by weight of centella asiatica; about 71% by weight of sodium acexamate; and about 14% by weight of sulfathiazole powder.

7. A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers according to claim 1 wherein the composition comprises about 14% by weight of centella asiatica; about 71% by weight of sodium acexamate; and about 14% by weight of ciprofloxacin.

8. A method for treatment of lower limb ulcers comprising administering to a subject in need a medicament comprising a pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) as claimed in claim 1.

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