Claims for Patent: 10,226,358

Summary for Patent: 10,226,358

Title:	Expandable spacer and method of use thereof
Abstract:	An expandable implant is disclosed having an adjustable height for insertion between two adjacent bony structures or joint surfaces, for example between two adjacent spinal vertebrae. The implant includes at least one gear associated with at least one threaded shaft. Rotation of the gear engages the threaded shaft to expand the implant. The implant can be inserted in a collapsed configuration and expanded in situ. The invention also provides methods for using the implant to facilitate arthrodesis or fusion of adjacent joint surfaces or spinal vertebrae.
Inventor(s):	Glerum; Chad (Pennsburg, PA)
Assignee:	Globus Medical, Inc. (Audubon, PA)
Application Number:	15/942,596
Patent Claims:	1. A method for facilitating fusion of two adjacent joint surfaces in a patient comprising the steps of: accessing a site in the patient's body having two adjacent joint surfaces to be fused; providing an expandable implant having a first collapsed height; preparing a space between the two adjacent joint surfaces for insertion of the implant; inserting the implant into the prepared space; wherein the expandable implant comprises: first and second threaded shafts; a base plate coupled to the first and second threaded shafts; a first gear and a second gear operably coupled to the first and second threaded shafts via threads disposed on an interior surface of the first and second gears that are matably engaged with the first and second threaded shafts, whereby rotation of at least one of the first and second gear initiates displacement of at least one of the first and second threaded shafts within said base plate, whereby the first and second threaded shafts are extendable in a direction away from the base plate; wherein the first and second threaded shafts are positioned with longitudinal axes oblique to the base plate and to one another, expanding the expandable implant; and closing the site in the patient's body. 2. The method of claim 1, further comprising a step of selecting a material for inserting through an opening in the first threaded shaft to fill a hollow interior of the first threaded shaft. 3. The method of claim 2, wherein the selecting step comprises selecting a bone graft material from the group consisting of autografts, allografts, xenografts, artificial mixtures, synthetic mixtures, demineralized bone matrix, hydroxyapatite mixtures, and combinations thereof. 4. The method of claim 3, wherein the selecting step further comprises selecting a growth factor or differentiation factor. 5. The method of claim 4, wherein the selecting step comprises selecting a growth factor from a group consisting of bone morphogenic protein (BMP), transforming growth factor 131 (TGF131), insulin-like growth factor 1 (IGF-1), platelet-derived growth factor (PDGF), activin, parathyroid hormone, fibroblast growth factor (FGF), LIM mineralization protein (LMP), and combinations thereof. 6. The method of claim 2, wherein a top end of the threaded shaft includes an opening, the opening operable for insertion of material into the hollow interior. 7. The method of claim 1, further comprising distracting the adjacent joint surfaces. 8. The method of claim 7, wherein the distracting the adjacent joint surfaces further comprises operating the implant in order to perform the distracting. 9. The method of claim 1, wherein the space is the intervertebral space between two adjacent spinal vertebrae. 10. A method for facilitating fusion of two adjacent joint surfaces in a patient comprising the steps of: accessing a site in the patient's body having two adjacent joint surfaces to be fused; providing an expandable implant having a first collapsed height; preparing a space between the two adjacent joint surfaces for insertion of the implant; inserting the implant into the prepared space; wherein the expandable implant comprises: first and second threaded shafts; a base plate coupled to the first and second threaded shafts; a first gear and a second gear operably coupled to the first and second threaded shafts via threads disposed on an interior surface of the first and second gears that are matably engaged with the first and second threaded shafts, whereby rotation of at least one of the first and second gear initiates displacement of at least one of the first and second threaded shafts within said base plate, whereby the first and second threaded shafts are extendable in a direction away from the base plate; wherein the first and second threaded shafts are positioned with longitudinal axes oblique to one another; expanding the expandable implant; and closing the site in the patient's body. 11. The method of claim 10, further comprising a step of selecting a material for inserting through an opening in the first threaded shaft to fill a hollow interior of the first threaded shaft. 12. The method of claim 11, wherein the selecting step comprises selecting a bone graft material from the group consisting of autografts, allografts, xenografts, artificial mixtures, synthetic mixtures, demineralized bone matrix, hydroxyapatite mixtures, and combinations thereof. 13. The method of claim 12, wherein the selecting step further comprises selecting a growth factor or differentiation factor. 14. The method of claim 13, wherein the selecting step comprises selecting a growth factor from a group consisting of bone morphogenic protein (BMP), transforming growth factor 131 (TGF131), insulin-like growth factor 1 (IGF-1), platelet-derived growth factor (PDGF), activin, parathyroid hormone, fibroblast growth factor (FGF), LIM mineralization protein (LMP), and combinations thereof. 15. The method of claim 10, wherein a top end of the threaded shaft includes an opening, the opening operable for insertion of material into the hollow interior.

Details for Patent 10,226,358

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Nps Pharmaceuticals, Inc.	NATPARA	parathyroid hormone	For Injection	125511	01/23/2015		2030-01-12