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Last Updated: December 17, 2025

Biologic Drugs With Established Pharmaceutical Class: Programmed Death Receptor-1 Blocking Antibody

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Biologic Drugs With Established Pharmaceutical Class: Programmed Death Receptor-1 Blocking Antibody

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Merck Sharp & Dohme Corp.	KEYTRUDA	pembrolizumab	For Injection	125514	2014-09-04	⤷ Get Started Free	⤷ Get Started Free
Bristol-myers Squibb Company	OPDIVO	nivolumab	Injection	125554	2014-12-22	⤷ Get Started Free	⤷ Get Started Free
Genentech, Inc.	TECENTRIQ	atezolizumab	Injection	761034	2016-05-18	⤷ Get Started Free	⤷ Get Started Free
Glaxosmithkline Llc	JEMPERLI	dostarlimab-gxly	Injection	761174	2021-04-22	⤷ Get Started Free	⤷ Get Started Free
Bristol-myers Squibb Company	OPDUALAG	nivolumab and relatlimab-rmbw	Injection	761234	2022-03-18	⤷ Get Started Free	⤷ Get Started Free
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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