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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR ALTEPLASE


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All Clinical Trials for alteplase

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000468 ↗ Myocardial Infarction Triage and Intervention Project (MITI) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1988-04-01 To determine the practicality, benefit, and safety of paramedic administration of thrombolytic therapy for acute myocardial infarction. The feasibility of paramedics correctly identifying candidates for thrombolytic therapy following myocardial infarction was assessed in Phase I. In Phase II, pre-hospital thrombolytic therapy was compared with in-hospital thrombolytic therapy.
NCT00000468 ↗ Myocardial Infarction Triage and Intervention Project (MITI) Completed University of Washington Phase 3 1988-04-01 To determine the practicality, benefit, and safety of paramedic administration of thrombolytic therapy for acute myocardial infarction. The feasibility of paramedics correctly identifying candidates for thrombolytic therapy following myocardial infarction was assessed in Phase I. In Phase II, pre-hospital thrombolytic therapy was compared with in-hospital thrombolytic therapy.
NCT00044057 ↗ A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator) Completed Astellas Pharma US, Inc. Phase 2 2000-12-01 The purpose of this study is to determine if YM872 in combination with t-PA can reduce disability and brain damage from stroke. YM872 or placebo will be given as a continuous intravenous (iv) infusion for 24 hours. It is important that the study medication, YM872 or placebo, is administered prior to the completion of the t-PA administration. The clinical effects of YM872 in addition to t-PA will be determined by assessing neurological function and disability scores at follow up visits through Day 90 of the study.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for alteplase

Condition Name

Condition Name for alteplase
Intervention Trials
Stroke 24
Ischemic Stroke 22
Acute Ischemic Stroke 21
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Condition MeSH

Condition MeSH for alteplase
Intervention Trials
Stroke 85
Ischemic Stroke 70
Ischemia 41
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Clinical Trial Locations for alteplase

Trials by Country

Trials by Country for alteplase
Location Trials
United States 255
China 155
Canada 32
Australia 19
United Kingdom 18
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Trials by US State

Trials by US State for alteplase
Location Trials
California 12
Illinois 11
Texas 11
Ohio 11
Maryland 10
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Clinical Trial Progress for alteplase

Clinical Trial Phase

Clinical Trial Phase for alteplase
Clinical Trial Phase Trials
Phase 4 20
Phase 3 47
Phase 2/Phase 3 13
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Clinical Trial Status

Clinical Trial Status for alteplase
Clinical Trial Phase Trials
Completed 50
Recruiting 35
Not yet recruiting 27
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Clinical Trial Sponsors for alteplase

Sponsor Name

Sponsor Name for alteplase
Sponsor Trials
Genentech, Inc. 17
Boehringer Ingelheim 11
Second Affiliated Hospital, School of Medicine, Zhejiang University 6
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Sponsor Type

Sponsor Type for alteplase
Sponsor Trials
Other 293
Industry 72
NIH 10
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