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Profile for Tradename: DEFINITY

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Definity is a drug marketed by Lantheus Medcl and is included in one NDA. It is available from one supplier. There are four patents protecting this drug.

The generic ingredient in DEFINITY is perflutren. One supplier is listed for this compound. Additional details are available on the perflutren profile page.

Summary for Tradename: DEFINITY

Suppliers: see list1

Pharmacology for Tradename: DEFINITY

Clinical Trials for: DEFINITY

A Prospective, Phase IV, Surveillance Registry Study to Evaluate the Safety of DEFINITY® in Clinical Practice
Status: Completed Condition: Cardiovascular Disease

Evaluation of Intra-operative Ultrasound Contrast Enhancement in the Evaluation of Liver Tumors
Status: Terminated Condition: Liver Tumors

A Study of Commercial DEFINITY® to Monitor the Effects of the Heart's Pulmonary Artery Pressure
Status: Completed Condition: Pulmonary Heart Disease

Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography
Status: Completed Condition: Pulmonary Arterial Hypertension

Contrast Enhanced Intraoperative Ultrasound for Detection and Characterization of Renal Mass Undergoing Open Partial Nephrectomy
Status: Completed Condition: Kidney Cancer

3-D Transcranial Ultrasound Analysis Study
Status: Completed Condition: Cerebrovascular Accident; Intracranial Hypertension

Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy
Status: Not yet recruiting Condition: Breast Cancer

Definity for Ultrasound of Intraocular Tumors
Status: Recruiting Condition: Ocular Melanoma

A Pilot Study of the Effects of Contrast Enhanced Endoscopic Ultrasound on Determining Vascular Involvement in Pancreatic Lesions
Status: Not yet recruiting Condition: Pancreatic Tumors

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
Status: Recruiting Condition: Hypertension

Courtesy of
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Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Lantheus Medcl
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes5,527,521<disabled>Y<disabled>
Lantheus Medcl
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes6,033,645<disabled><disabled>
Lantheus Medcl
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,658,205<disabled>Y<disabled>
Lantheus Medcl
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,685,441<disabled><disabled>
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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