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Profile for Tradename: INOMAX

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Inomax is a drug marketed by INO and is included in one NDA. It is available from one supplier. There are thirteen patents protecting this drug and one Paragraph IV challenge.

The generic ingredient in INOMAX is nitric oxide. There are six drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the nitric oxide profile page.

Summary for Tradename: INOMAX

Patents:13
Applicants:1
NDAs:1
Suppliers / Packagers: see list4

Pharmacology for Tradename: INOMAX

Drug ClassVasodilator
Physiological EffectVasodilation

Clinical Trials for: INOMAX

Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children
Status: Completed Condition: Acute Chest Syndrome; Sickle Cell Disease

Comparison of Inhaled Nitric Oxide and Oxygen in Patient Reactivity During Acute Pulmonary Vasodilator Testing
Status: Completed Condition: Idiopathic Pulmonary Arterial Hypertension; Congenital Heart Disease With Pulmonary Hypertension; Cardiomyopathy

Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation
Status: Recruiting Condition: Liver Transplantation; Ischemia/Reperfusion Injury; Oxidative Injury

Nitric Oxide Administration for Acute Respiratory Distress Syndrome
Status: Completed Condition: Acute Respiratory Distress Syndrome

The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation
Status: Completed Condition: Congestive Heart Failure

Use of Inhaled Nitric Oxide to Prevent Pulmonary Hypertension Associated to Stored Blood Transfusion
Status: Not yet recruiting Condition: Hypertension, Pulmonary; Hemolysis

Inhaled Nitric Oxide to Prevent and Treat Bronchopulmonary Dysplasia
Status: Completed Condition: Pulmonary Disease

RATNO, Reducing Antibiotic Tolerance Using Nitric Oxide in CF - a Phase 2 Pilot Study
Status: Completed Condition: Cystic Fibrosis

Inhaled Nitric Oxide (INO) In Hypoxic Respiratory Failure
Status: Withdrawn Condition: Hypoxic Respiratory Failure With Pulmonary Hypertension

Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD Placement
Status: Recruiting Condition: Heart Failure

Courtesy of ClinicalTrials.org
See more clinical trials for this drug
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ino
INOMAX
nitric oxide
GAS;INHALATION020845-002Dec 23, 1999DISCNNo8,573,210*PED<disabled>Y<disabled>
Ino
INOMAX
nitric oxide
GAS;INHALATION020845-003Dec 23, 1999RXYes8,795,741*PED<disabled>Y<disabled>
Ino
INOMAX
nitric oxide
GAS;INHALATION020845-003Dec 23, 1999RXYes8,282,966*PED<disabled>Y<disabled>
Ino
INOMAX
nitric oxide
GAS;INHALATION020845-002Dec 23, 1999DISCNNo8,776,795*PED<disabled>Y<disabled>
Ino
INOMAX
nitric oxide
GAS;INHALATION020845-002Dec 23, 1999DISCNNo8,573,209*PED<disabled>Y<disabled>
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Paragraph IV activity for: INOMAX

Drugname Dosage Strength RLD Submissiondate
nitric oxidefor Inhalation100 ppm and 800 ppmINOmax5/20/2014
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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