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Profile for Tradename: DEFINITY

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Definity is a drug marketed by Lantheus Medcl and is included in one NDA. It is available from one supplier. There are four patents protecting this drug.

This drug has one hundred and eight patent family members in thirty countries.

The generic ingredient in DEFINITY is perflutren. One supplier is listed for this compound. Additional details are available on the perflutren profile page.

Summary for Tradename: DEFINITY

Patents:4
Applicants:1
NDAs:1
Suppliers / Packagers: see list3

Pharmacology for Tradename: DEFINITY

Clinical Trials for: DEFINITY

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes5,527,521<disabled>Y<disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,658,205<disabled>Y<disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes6,033,645<disabled><disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,685,441<disabled><disabled>
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Non-Orange Book Patents for Tradename: DEFINITY

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,329,402Methods of imaging and treatment<disabled in preview>
5,736,121 Stabilized homogenous suspensions as computed tomography contrast agents<disabled in preview>
5,205,290 Low density microspheres and their use as contrast agents for computed tomography<disabled in preview>
5,874,062 Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents<disabled in preview>
5,547,656 Low density microspheres and their use as contrast agents for computed tomography, and in other applications<disabled in preview>
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International Patent Family for Tradename: DEFINITY

Country Document Number Publication Date
Germany69941634Dec 24, 2009
Spain2134214Mar 01, 2009
Denmark0804932Aug 06, 2001
TaiwanI242448Nov 01, 2005
European Patent Office0580726Mar 29, 1995
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.

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Copyright 2002-2015 thinkBiotech LLC
ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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