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Patent: 6,818,229

Summary for Patent: 6,818,229

Title: Intermediate release nicotinic acid compositions for treating hyperlipidemia
Abstract:Intermediate release nicotinic acid formulations having unique biopharmaceutical characteristics, such as Cmax, Tmax and AUC, which are suitable for oral administration once per day during the evening or at night for treating hyperlipidemia without causing drug-induced hepatotoxicity to such a level that requires the therapy to be discontinued, are disclosed. The intermediate nicotinic acid formulations can be administered as tablets in dosage strengths of, for example, 375 mg, 500 mg, 750 mg and 1000 mg.
Inventor(s): Cefali; Eugenio A. (Fort Lauderdale, FL), Bova; David J. (Boca Raton, FL)
Assignee: KOS Pharmaceuticals, Inc. (Miami, FL)
Application Number:08/962,027
Patent Claim Types:
see list of patent claims
Use; Formulation; Compound; Dosage form;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Abbvie
ADVICOR
lovastatin; niacin
TABLET, EXTENDED RELEASE;ORAL021249Dec 17, 2001RXYes6,818,229<disabled>Y
Abbvie
ADVICOR
lovastatin; niacin
TABLET, EXTENDED RELEASE;ORAL021249Apr 27, 2006RXYes6,818,229<disabled>Y
Abbvie
NIASPAN
niacin
TABLET, EXTENDED RELEASE;ORAL020381Jul 28, 1997RXYes6,818,229<disabled>Y
Abbvie
NIASPAN
niacin
TABLET, EXTENDED RELEASE;ORAL020381Jul 28, 1997DISCNNo6,818,229<disabled>Y
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International Patent Family for Patent: 6,818,229

Country Document Number Publication Date
Austria289197Mar 15, 2005
Australia775967Aug 19, 2004
Australia4751802Aug 01, 2002
Australia6348198Sep 22, 1998
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