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Patent: 6,403,649

Summary for Patent: 6,403,649

Title: Non-acidic cyclopentane heptanoic acid,2-cycloalkyl or arylalkyl derivatives as therapeutic agents
Abstract:The present invention provides cydopentane heptanoic acid, 2-cycloalkyl or arylalkyl compounds, which may be substituted in the 1-position with amino, amido, ether or ester groups, e.g., a 1-OH cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compound. The cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma. Moreover, the cydopentane heptanoic, 2-(cycloalkyl or arylalkyl) compounds of this invention are smooth muscle relaxants with broad application in systemic hypertensive and pulmonary diseases; smooth muscle relaxants with application in gastrointestinal disease, reproduction, fertility, incontinence, shock, etc.
Inventor(s): Woodward; David F. (El Toro, CA), Andrews; Steven W. (Rancho Santa Marguerita, CA), Burk; Robert M. (Irvine, CA), Garst; Michael E. (Newport Beach, CA)
Assignee: Allergan Sales, Inc. (Irvine, CA)
Application Number:09/519,834
Patent Claim Types:
see list of patent claims
Compound; Use;
Patent PDF download available with subscription

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International Patent Family for Patent: 6,403,649

Country Document Number Publication Date
WIPO (PCT)9406433Mar 31, 1994
WIPO (PCT)9636599Nov 21, 1996
WIPO (PCT)9730710Aug 28, 1997
United States5352708Oct 04, 1994
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