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DrugPatentWatch concentrates deep knowledge on more than 6,400 small-molecule drugs and 2,300 generic ingredients from 1,700 branded and generic pharmaceutical companies and 700 suppliers, and more than 4,300 active and expired US patents and 74,000 international patents spanning 93 countries and regional patent offices. |
| Title: | Recombinant heterodimeric human fertility hormones, and methods, cells, and vectors and DNA for the production thereof |
| Abstract: | Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subunit being controlled by a separate promoter. Preferred human fertility hormones include hCG, hLH and hFSH. |
| Inventor(s): | Reddy; Vermuri B. (Westboro, MA), Hsiung; Nancy (Wellesley, MA), Beck; Anton K. (Grisbeladierbeg, CH), Bernstine; Edward George (Boston, MA) |
| Assignee: | Genzyme Corporation (Cambridge, MA) |
| Application Number: | 08/008,233 |
| Patent Claim Types: see list of patent claims | Compound; |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Type | RLD | Patent No. | Product | Substance | Delist_Flag | Patent Expiration | Patented / Exclusive Use | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Emd Serono | LUVERIS | lutropin alfa | INJECTABLE; SUBCUTANEOUS | 021322 | Oct 8, 2004 | DISCN | No | 5,767,251 | Y | <disabled> | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Emd Serono | GONAL-F RFF PEN | follitropin alfa/beta | INJECTABLE; SUBCUTANEOUS | 021684 | May 25, 2004 | RX | Yes | 5,767,251 | Y | <disabled> | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Emd Serono | GONAL-F RFF | follitropin alfa/beta | INJECTABLE; SUBCUTANEOUS | 021765 | Mar 25, 2004 | RX | Yes | 5,767,251 | Y | <disabled> | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Emd Serono | GONAL-F | follitropin alfa/beta | INJECTABLE; SUBCUTANEOUS | 020378 | Sep 29, 1997 | DISCN | No | 5,767,251 | Y | <disabled> | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Country | Document Number | Publication Date | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| WIPO (PCT) | 8501958 | May 09, 1985 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| WIPO (PCT) | 8501959 | May 09, 1985 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| WIPO (PCT) | 8604589 | Aug 14, 1986 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| United States | 2003059898 | Mar 27, 2003 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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