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Patent: 5,747,472

Summary for Patent: 5,747,472

Title: Therapeutic methods for using ARA-G derivatives
Abstract:6-Alkoxy derivatives of Ara-G, and pharmaceutically acceptable esters thereof, are described as being useful in tumour therapy. Novel pharmaceutically acceptable esters, their preparation and pharmaceutical formulations containing them are also disclosed.
Inventor(s): Krenitsky; Thomas Anthony (Chapel Hill, NC), Averett; Devron Randolph (Raleigh, NC), Koszalka; George Walter (Chapel Hill, NC), Wolberg; Gerald (Cary, NC)
Assignee: Glaxo Wellcome Inc. (Research Triangle Park, NC)
Application Number:08/456,186
Patent Claim Types:
see list of patent claims
Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Product Substance Delist_Flag Patent Expiration Patented / Exclusive Use
Smithkline Beecham
ARRANON
nelarabine
INJECTABLE; IV (INFUSION)021877Oct 28, 2005RXYes5,747,472<disabled>TREATMENT OF PATIENTS WITH T-CELL LYMPHOBLASTIC LYMPHOMA WHOSE DISEASE HAS NOT RESPONDED TO OR HAS RELAPSED FOLLOWING TREATMENT WITH AT LEAST TWO CHEMOTHERAPY REGIMENS
Smithkline Beecham
ARRANON
nelarabine
INJECTABLE; IV (INFUSION)021877Oct 28, 2005RXYes5,747,472<disabled>TREATMENT OF PATIENTS WITH T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND T-CELL LYMPHOBLASTIC LYMPHOMA WHOSE DISEASE HAS NOT RESPONDED TO OR HAS RELAPSED FOLLOWING TREATMENT WITH AT LEAST TWO CHEMOTHERAPY REGIMENS
Smithkline Beecham
ARRANON
nelarabine
INJECTABLE; IV (INFUSION)021877Oct 28, 2005RXYes5,747,472<disabled>TREATMENT OF PATIENTS WITH T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA WHOSE DISEASE HAS NOT RESPONDED TO OR HAS RELAPSED FOLLOWING TREATMENT WITH AT LEAST TWO CHEMOTHERAPY REGIMENS
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Foreign Priority and PCT Information for Patent: 5,747,472

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9015914Jul 19, 1990

International Patent Family for Patent: 5,747,472

Country Document Number Publication Date
South Africa9105656Mar 31, 1993
WIPO (PCT)9201456Feb 06, 1992
United States5492897Feb 20, 1996
United States5821236Oct 13, 1998
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