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Patent: 5,629,327

Summary for Patent: 5,629,327

Title: Methods and compositions for inhibition of angiogenesis
Abstract:The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
Inventor(s): D'Amato; Robert (Lancaster, PA)
Assignee: Childrens Hospital Medical Center Corp. (Boston, MA)
Application Number:08/168,817
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Celgene
THALOMID
thalidomide
CAPSULE;ORAL020785Jul 16, 1998RXNo5,629,327<disabled>USE IN COMBINATION WITH DEXAMETHASONE IS INDICATED FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
Celgene
THALOMID
thalidomide
CAPSULE;ORAL020785Jan 17, 2003RXNo5,629,327<disabled>USE IN COMBINATION WITH DEXAMETHASONE IS INDICATED FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
Celgene
THALOMID
thalidomide
CAPSULE;ORAL020785Jan 10, 2007RXNo5,629,327<disabled>USE IN COMBINATION WITH DEXAMETHASONE IS INDICATED FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
Celgene
THALOMID
thalidomide
CAPSULE;ORAL020785Jan 17, 2003RXYes5,629,327<disabled>USE IN COMBINATION WITH DEXAMETHASONE IS INDICATED FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
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International Patent Family for Patent: 5,629,327

Country Document Number Publication Date
Austria304356Sep 15, 2005
Austria218865Jun 15, 2002
Australia6248694Sep 26, 1994
Australia676722Sep 26, 1994
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