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Patent: 5,538,739

Summary for Patent: 5,538,739

Title: Sustained release formulations of water soluble peptides
Abstract:The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
Inventor(s): Bodmer; David (Klingnau, CH), Fong; Jones W. (Parsippany, NJ), Kissel; Thomas (Staufen, DE), Maulding, Jr.; Hawkins V. (Mendham, NJ), Nagele; Oskar (Sissach, CH), Pearson; Jane E. (Ogendensburg, NJ)
Assignee: Sandoz Ltd. (Basel, CH)
Application Number:07/643,880
Patent Claim Types:
see list of patent claims
Compound; Formulation;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Novartis
SANDOSTATIN LAR
octreotide acetate
INJECTABLE;INJECTION021008Nov 25, 1998RXYes5,538,739*PED<disabled>Y
Novartis
SANDOSTATIN LAR
octreotide acetate
INJECTABLE;INJECTION021008Nov 25, 1998RXNo5,538,739*PED<disabled>Y
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Foreign Priority and PCT Information for Patent: 5,538,739

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Hungary3974/90Jun 25, 1990
United Kingdom9016840Aug 01, 1990

International Patent Family for Patent: 5,538,739

Country Document Number Publication Date
South Africa9005327Mar 25, 1992
South Africa9106070Apr 28, 1993
United States5639480Jun 17, 1997
United States5688530Nov 18, 1997
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