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Patent: 5,474,979

Summary for Patent: 5,474,979

Title: Nonirritating emulsions for sensitive tissue
Abstract:A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.
Inventor(s): Ding; Shulin (Irvine, CA), Tien; Walter L. (Irvine, CA), Olejnik; Orest (Trabuco Canyon, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:08/243,279
Patent Claim Types:
see list of patent claims
Composition; Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Allergan
RESTASIS
cyclosporine
EMULSION;OPHTHALMIC050790Dec 23, 2002RXYes5,474,979<disabled>Y
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Patent activity for: 5,474,979

Ex parte reexamination
Filing: 5,474,979, Reexam. C.N. 90/009,944, Requested Date: Aug. 27, 2011, Cl. 514/011, Title: NONIRRITATING EMULSIONS FOR SENSITIVE TISSUE, Inventor: Shulin Ding et al., Owners of Record: Allergan, Inc., Irvine, CA, Attorney or Agent: Walter A. Hackler, Newport Beach, CA, Ex. Gp.: 3991, Requester: John Burr, PharmGen, LLC., Phoenix, AZ

International Patent Family for Patent: 5,474,979

Country Document Number Publication Date
WIPO (PCT)9531211Nov 23, 1995
Portugal1044678Aug 29, 2003
Portugal759773Feb 28, 2002
New Zealand287635Sep 24, 1998
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