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Patent: 5,447,926

Summary for Patent: 5,447,926

Title: Quinolone carboxylic acid derivatives
Abstract:A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R.sup.1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R.sup.2 is a hydrogen atom or an amino group which may be substituted by one or two lower alkyl groups, X is a hydrogen atom or a halogen atom, Y is CH.sub.2, O, S, SO, SO.sub.2, or N--R.sup.3, wherein R.sup.3 is a hydrogen atom or a lower alkyl group, and Z is an oxygen atom or two hydrogen atoms; or a salt thereof; and an antimicrobial agent comprising the same. The compound exhibits a superior antimicrobial activity, especially against gram positive microorganisms, and is thus useful for the treatments and prevention of various infectious diseases in clinics.
Inventor(s): Konno; Fujiko (Tomisato, JP), Shibata; Akihiro (Yachiyo, JP), Matsuda; Hideaki (Abiko, JP), Asaoka; Takemitsu (Narita, JP), Kawahara; Ryuichi (Ichikawa, JP), Taido; Naokata (Funabashi, JP), Kuraishi; Tasdayuki (Chiba, JP), Takeda; Sunao (Ichihara, JP)
Assignee: SS Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:08/305,977
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Product Substance Delist_Flag Patent Expiration Patented / Exclusive Use
Bausch And Lomb
BESIVANCE
besifloxacin hydrochloride
SUSPENSION/DROPS; OPHTHALMIC022308May 28, 2009RXYes5,447,926YY<disabled>METHOD OF TREATING OCULAR BACTERIAL INFECTIONS
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Foreign Priority and PCT Information for Patent: 5,447,926

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2-191339Jul 19, 1990
Japan3-079774Apr 12, 1991

International Patent Family for Patent: 5,447,926

Country Document Number Publication Date
WIPO (PCT)9201676Feb 06, 1992
United States5385900Jan 31, 1995
Japan2613139May 21, 1997
Japan2805460Sep 30, 1998
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