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| Title: | Terazosin monohydrochloride and processes and intermediate for its production |
| Abstract: | The present invention provides a non-solvated crystalline polymorph of terazosin monohydrochloride designated Form III and methods for its preparation. Also disclosed is terazosin monohydrochloride methanolate and processes for its production as well as processes for its conversion to other crystalline forms of terazosin monohydrochloride. |
| Inventor(s): | Morley; James A. (Gurnee, IL), Bauer; John F. (Lake Bluff, IL), Patel; Ramesh F. (Chicago, IL), Henry; Rodger E. (Waukegan, IL), Spanton; Stephen G. (Grayslake, IL) |
| Assignee: | Abbott Laboratories (Abbott Park, IL) |
| Application Number: | 08/246,526 |
| Patent Claim Types: see list of patent claims | Compound; |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Type | RLD | Patent No. | Patent Expiration | Patented / Exclusive Use | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Abbott | HYTRIN | terazosin hydrochloride | CAPSULE; ORAL | 020347 | Dec 14, 1994 | RX | No | 5,412,095 | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abbott | HYTRIN | terazosin hydrochloride | CAPSULE; ORAL | 020347 | Dec 14, 1994 | RX | Yes | 5,412,095 | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abbott | HYTRIN | terazosin hydrochloride | TABLET; ORAL | 019057 | Aug 7, 1987 | RX | No | 5,412,095 | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abbott | HYTRIN | terazosin hydrochloride | TABLET; ORAL | 019057 | Aug 7, 1987 | RX | Yes | 5,412,095 | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Country | Document Number | Publication Date | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Austria | 130853 | Dec 15, 1995 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Austria | 182592 | Aug 15, 1999 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Canada | 2107382 | Oct 30, 1994 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Canada | 2143974 | Nov 21, 1995 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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