
| Title: | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-c arboxylate and compositions and methods of pharmaceutical use thereof |
| Abstract: | 1-(Cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-car boxylate or a pharmaceutically acceptable salt thereof has potent angiotensin II antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc. |
| Inventor(s): | Naka; Takehiko (Kobe, JP), Nishikawa; Kohei (Kyoto, JP), Kato; Takeshi (Higashiosaka, JP) |
| Assignee: | Takeda Chemical Industries, Ltd. (Osaka, JP) |
| Application Number: | 07/687,238 |
| Patent Claim Types: | Compound; Composition; Use; |
| Applicant | Tradename | Generic Name | NDA | Approval Date | Type | RLD | Patent Number | Product | Substance | Delist Req. | Patent Expiration | Patented / Exclusive Use |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Astrazeneca | ATACAND | candesartan cilexetil | 020838 | Jun 4, 1998 | RX | No | 5,196,444*PED | Y | Dec 4, 2012 | |||
| Astrazeneca | ATACAND | candesartan cilexetil | 020838 | Jun 4, 1998 | RX | Yes | 5,196,444*PED | Y | Dec 4, 2012 | |||
| Astrazeneca | ATACAND HCT | candesartan cilexetil; hydrochlorothiazide | 021093 | Sep 5, 2000 | RX | No | 5,196,444*PED | Y | Dec 4, 2012 |
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