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DrugPatentWatch concentrates deep knowledge on more than 6,400 small-molecule drugs and 2,300 generic ingredients from 1,700 branded and generic pharmaceutical companies and 700 suppliers, and more than 4,300 active and expired US patents and 74,000 international patents spanning 93 countries and regional patent offices. |
| Title: | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-c arboxylate and compositions and methods of pharmaceutical use thereof |
| Abstract: | 1-(Cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-car boxylate or a pharmaceutically acceptable salt thereof has potent angiotensin II antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc. |
| Inventor(s): | Naka; Takehiko (Kobe, JP), Nishikawa; Kohei (Kyoto, JP), Kato; Takeshi (Higashiosaka, JP) |
| Assignee: | Takeda Chemical Industries, Ltd. (Osaka, JP) |
| Application Number: | 07/687,238 |
| Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Type | RLD | Patent No. | Product | Substance | Delist_Flag | Patent Expiration | Patented / Exclusive Use | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Astrazeneca | ATACAND HCT | candesartan cilexetil; hydrochlorothiazide | TABLET; ORAL | 021093 | May 16, 2008 | RX | Yes | 5,196,444*PED | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Astrazeneca | ATACAND HCT | candesartan cilexetil; hydrochlorothiazide | TABLET; ORAL | 021093 | Sep 5, 2000 | RX | No | 5,196,444*PED | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Astrazeneca | ATACAND | candesartan cilexetil | TABLET; ORAL | 020838 | Jun 4, 1998 | RX | No | 5,196,444*PED | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Astrazeneca | ATACAND | candesartan cilexetil | TABLET; ORAL | 020838 | Jun 4, 1998 | RX | Yes | 5,196,444*PED | <disabled> | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| South Africa | 9102983 | Jan 29, 1992 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| United States | 2001047020 | Nov 29, 2001 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| United States | 2002151723 | Oct 17, 2002 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| United States | 2004044223 | Mar 04, 2004 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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