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Patent: 5,196,444

Summary for Patent: 5,196,444

Title: 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-c arboxylate and compositions and methods of pharmaceutical use thereof
Abstract:1-(Cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-car boxylate or a pharmaceutically acceptable salt thereof has potent angiotensin II antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc.
Inventor(s): Naka; Takehiko (Kobe, JP), Nishikawa; Kohei (Kyoto, JP), Kato; Takeshi (Higashiosaka, JP)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:07/687,238
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Product Substance Delist_Flag Patent Expiration Patented / Exclusive Use
Astrazeneca
ATACAND HCT
candesartan cilexetil; hydrochlorothiazide
TABLET; ORAL021093May 16, 2008RXYes5,196,444*PED<disabled>
Astrazeneca
ATACAND HCT
candesartan cilexetil; hydrochlorothiazide
TABLET; ORAL021093Sep 5, 2000RXNo5,196,444*PED<disabled>
Astrazeneca
ATACAND
candesartan cilexetil
TABLET; ORAL020838Jun 4, 1998RXNo5,196,444*PED<disabled>
Astrazeneca
ATACAND
candesartan cilexetil
TABLET; ORAL020838Jun 4, 1998RXYes5,196,444*PED<disabled>
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Foreign Priority and PCT Information for Patent: 5,196,444

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2-113148Apr 27, 1990
Japan2-141942May 30, 1990
Japan2-208662Aug 06, 1990
Japan2-264579Oct 01, 1990

International Patent Family for Patent: 5,196,444

Country Document Number Publication Date
South Africa9102983Jan 29, 1992
United States2001047020Nov 29, 2001
United States2002151723Oct 17, 2002
United States2004044223Mar 04, 2004
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