|Title:||1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-c arboxylate and compositions and methods of pharmaceutical use thereof|
|Abstract:||1-(Cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-car boxylate or a pharmaceutically acceptable salt thereof has potent angiotensin II antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc.|
|Inventor(s):||Naka; Takehiko (Kobe, JP), Nishikawa; Kohei (Kyoto, JP), Kato; Takeshi (Higashiosaka, JP)|
|Assignee:||Takeda Chemical Industries, Ltd. (Osaka, JP)|
|Patent Claim Types:|
see list of patent claims
|Compound; Composition; Use;|
|Country||Document Number||Publication Date|
|South Africa||9102983||Jan 29, 1992|
|United States||5328919||Jul 12, 1994|
|United States||5401764||Mar 28, 1995|
|United States||5703110||Dec 30, 1997|
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