Last Updated: June 9, 2026

Details for Patent: 5,403,833

Name: Drug Patent Intelligence for US Patent 5403833
Creator: DrugPatentWatch
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Summary for Patent: 5,403,833

Title:	Methods of inhibiting transplant rejecton in mammals using rapamycin and derivatives and prodrugs thereof
Abstract:	This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
Inventor(s):	Sir Roy Calne
Assignee:	Individual
Application Number:	US08/192,648
Patent Claim Types: see list of patent claims	Use; Delivery;

Drugs Protected by US Patent 5,403,833

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 5,403,833

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0401747	⤷ Start Trial	CA 2001 00025	Denmark	⤷ Start Trial
European Patent Office	0401747	⤷ Start Trial	SPC/GB01/036	United Kingdom	⤷ Start Trial
European Patent Office	0401747	⤷ Start Trial	25/2001	Austria	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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