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|Title:||Intermediate release nicotinic acid compositions for treating hyperlipidemia|
|Abstract:||Intermediate release nicotinic acid formulations having unique biopharmaceutical characteristics, such as Cmax, Tmax and AUC, which are suitable for oral administration once per day during the evening or at night for treating hyperlipidemia without causing drug-induced hepatotoxicity to such a level that requires the therapy to be discontinued, are disclosed. The intermediate nicotinic acid formulations can be administered as tablets in dosage strengths of, for example, 375 mg, 500 mg, 750 mg and 1000 mg.|
|Inventor(s):||Cefali; Eugenio A. (Fort Lauderdale, FL), Bova; David J. (Boca Raton, FL)|
|Assignee:||KOS Pharmaceuticals, Inc. (Miami, FL)|
Patent Claim Types:|
see list of patent claims
|Use; Formulation; Compound; Dosage form;|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Finland||119910||May 15, 2009|
|Brazil||9815454||Oct 23, 2001|
|World Intellectual Property Organization (WIPO)||9839002||Sep 11, 1998|
|Canada||2283322||Sep 11, 1998|
|Finland||991896||Sep 22, 1999|
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