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Details for Patent: 6,395,293

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Patent 6,395,293 protects ELIGARD and is included in four NDAs.

Summary for Patent: 6,395,293

Title: Biodegradable implant precursor
Abstract:The invention is directed to a biodegradable implant precursor having a two-part structure made of an outer sac and a liquid content. The implant precursor is composed of a biodegradable, water-coagulable thermoplastic polymer and a water-miscible organic solvent. When administered to an implant site in an animal, the implant precursor will solidify in situ to a solid, microporous matrix by dissipation of the organic solvent to surrounding tissue fluids and coagulation of the polymer. The invention also includes methods of making the implant precursor, an apparatus for forming the precursor, and a kit containing the apparatus. Also provided are methods of using the implant precursor for treating a tissue defect in an animal, for example, for enhancing cell growth and tissue regeneration, wound and organ repair, nerve regeneration, soft and hard tissue regeneration, and the like, for delivery of biologically-active substances to tissue or organs, and other like therapies.
Inventor(s): Polson; Alan M. (Fort Collins, CO), Swanbom; Deryl D. (Fort Collins, CO), Dunn; Richard L. (Fort Collins, CO), Cox; Charles P. (Fort Collins, CO), Norton; Richard L. (Fort Collins, CO), Lowe; Bryan K. (Fort Collins, CO), Peterson; Kenneth S. (Fort Collins, CO)
Assignee: Atrix Laboratories (Fort Collins, CO)
Application Number:09/520,735
Patent Claim Types:
see list of patent claims
Device; Formulation;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Tolmar Therap
ELIGARD
leuprolide acetate
INJECTABLE;SUBCUTANEOUS021343Jan 23, 2002RXYes6,395,293<disabled>YMETHOD OF TREATING CANCER
Tolmar Therap
ELIGARD
leuprolide acetate
INJECTABLE;SUBCUTANEOUS021379Jul 24, 2002RXYes6,395,293<disabled>Y
Tolmar Therap
ELIGARD
leuprolide acetate
INJECTABLE;SUBCUTANEOUS021488Feb 13, 2003RXYes6,395,293<disabled>Y
Tolmar Therap
ELIGARD
leuprolide acetate
INJECTABLE;SUBCUTANEOUS021731Dec 14, 2004RXYes6,395,293<disabled>Y
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International Patent Family for Patent: 6,395,293

Country Document Number Publication Date
World Intellectual Property Organization (WIPO)9101126Feb 07, 1991
United States of America2002001608Jan 03, 2002
United States of America6071530Jun 06, 2000
United States of America5660849Aug 26, 1997
United States of America5599552Feb 04, 1997
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