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Details for Patent: 6,280,705

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Summary for Patent: 6,280,705

Title: Kits & systems for ultrasonic imaging
Abstract:A gas emulsion forming composition comprising a dry, hollow, particulate, approximately microspherical material permeated with a gas or gas mixture, which upon dissolution in aqueous liquid forms a gas emulsion comprising a plurality of bubbles surrounded by a layer of at least a first and a second surfactant, wherein the first surfactant consists essentially of a phospholipid or mixture of phospholipids having at least one acyl chain which comprises at least 10 carbon atoms, and comprising at least about 5% w/w of total surfactant, and wherein the second surfactant may or may not be a phospholipid and is more water soluble than the first surfactant; kits for preparing such microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s): Trevino; Leo A. (San Diego, CA), Schutt; Ernest George (San Diego, CA), Klein; David H. (Carlsbad, CA), Tarara; Thomas E. (San Diego, CA), Weers; Jeffry G. (San Diego, CA), Kabalnov; Alexey (San Diego, CA)
Assignee: Alliance Pharmaceutical Corp. (San Diego, CA)
Application Number:09/013,357
Patent Claim Types:
see list of patent claims
Device; Formulation; Delivery;
Patent PDF download available with subscription

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International Patent Family for Patent: 6,280,705

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Hungary9802095Jan 28, 1999
European Patent Office0711179Sep 01, 2010
Norway973489Jul 30, 1997
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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