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Details for Patent: 6,187,791

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Summary for Patent: 6,187,791

Title: Method of providing an antihistaminic effect in a hepatically impaired patient
Abstract:The present invention relates to a method of providing an antihistaminic effect in a hepatically impaired patient in need thereof comprising administering to said patient an effective antihistaminic amount of a compound of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxy; R.sub.2 is hydrogen; or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2; n is an integer of from 1 to 5; R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; each of A and B is hydrogen or hydroxy with the proviso that at least one of A or B is hydrogen; or a pharmaceutically acceptable salt and individual isomers thereof.
Inventor(s): Woodward; James K. (Cincinnati, OH), Okerholm; Richard A. (West Chester, OH), Eller; Mark G. (Overland Park, KS), McNutt; Bruce E. (Olathe, KS)
Assignee: Merrell Pharmaceuticals Inc. (Bridgewater, NJ)
Application Number:09/481,404
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

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International Patent Family for Patent: 6,187,791

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Hungary223774Jan 28, 2005
Canada2134211Nov 25, 1993
Spain2121084Nov 16, 1998
Austria194913Aug 15, 2000
Norway307688May 15, 2000
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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