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Details for Patent: 6,015,819

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Patent 6,015,819 protects and is included in zero NDA.

Summary for Patent: 6,015,819

Title: Use of alpha-1C specific compounds to treat benign prostatic hyperplasia
Abstract:A method of treating benign prostatic hyperplasia in a subject which comprises administering to the subject a therapeutically effective amount of a compound which binds to a human .alpha..sub.1C adrenergic receptor with a binding affinity greater than ten-fold higher than the binding affinity with which the compound binds to a human .alpha..sub.1A adrenergic receptor, a human .alpha..sub.1B adrenergic receptor, and a human histamine H.sub.1 receptor, and, binds to a human .alpha..sub.2 adrenergic receptor with a binding affinity which is greater than ten-fold lower than the binding affinity with which the compound binds to such .alpha..sub.1C adrenergic receptor. Compounds meeting these criteria are provided.
Inventor(s): Gluchowski; Charles (Danville, CA), Forray; Carlos C. (Paramus, NJ), Chiu; George (Bridgewater, NJ), Branchek; Theresa A. (Teaneck, NJ), Wetzel; John M. (Elmwood Park, NJ), Hartig; Paul R. (Pennington, NJ)
Assignee: Synaptic Pharmaceutical Corporation (Paramus, NJ)
Application Number:08/244,354
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Foreign Priority and PCT Information for Patent: 6,015,819

PCT Information
PCT FiledNovember 12, 1993PCT Application Number:PCT/US93/10950
PCT Publication Date:May 26, 1994PCT Publication Number: WO94/10989

International Patent Family for Patent: 6,015,819

Country Document Number Publication Date
South Africa9308510Aug 02, 1994
South Africa9502763Jan 05, 1996
World Intellectual Property Organization (WIPO)9410989May 26, 1994
World Intellectual Property Organization (WIPO)9507075Mar 16, 1995
World Intellectual Property Organization (WIPO)9528157Oct 26, 1995
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