Details for Patent: 5,814,335
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Summary for Patent: 5,814,335
Title: | Sphingosomes for enhanced drug delivery |
Abstract: | Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of ciprofloxacin, and alkaloid drugs, particularly swainsonine, vincristine and vinblastine, is significantly improved. |
Inventor(s): | Webb; Murray S. (Vancouver, CA), Bally; Marcel B. (Bowen Island, CA), Mayer; Lawrence D. (N. Vancouver, CA), Miller; James J. (Vancouver, CA), Tardi; Paul G. (Richmond, CA) |
Assignee: | Inex Pharmaceuticals Corporation (CA) |
Application Number: | 08/932,375 |
Patent Claim Types: see list of patent claims | Compound; Dosage form; Process; Delivery; Formulation; Composition; |
Drugs Protected by US Patent 5,814,335
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International Family Members for US Patent 5,814,335
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | 248586 | ⤷ Try a Trial | |||
Australia | 2709495 | ⤷ Try a Trial | |||
Canada | 2193502 | ⤷ Try a Trial | |||
Germany | 69531701 | ⤷ Try a Trial | |||
European Patent Office | 0804159 | ⤷ Try a Trial | |||
Spain | 2206510 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |