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Details for Patent: 5,767,251

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Patent 5,767,251 protects OVIDREL, FOLLISTIM, FOLLISTIM AQ, GONAL-F, GONAL-F RFF, GONAL-F RFF REDI-JECT, and LUVERIS, and is included in eight NDAs.

Summary for Patent: 5,767,251

Title: Recombinant heterodimeric human fertility hormones, and methods, cells, and vectors and DNA for the production thereof
Abstract:Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subunit being controlled by a separate promoter. Preferred human fertility hormones include hCG, hLH and hFSH.
Inventor(s): Reddy; Vermuri B. (Westboro, MA), Hsiung; Nancy (Wellesley, MA), Beck; Anton K. (Grisbeladierbeg, CH), Bernstine; Edward George (Boston, MA)
Assignee: Genzyme Corporation (Cambridge, MA)
Application Number:08/008,233
Patent Claim Types:
see list of patent claims
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Emd Serono
choriogonadotropin alfa
INJECTABLE;INJECTION021149Sep 20, 2000DISCNNo5,767,251<disabled>
Organon Usa Inc
follitropin alfa/beta
Organon Usa Inc
follitropin alfa/beta
INJECTABLE;SUBCUTANEOUS021273Aug 26, 2005RXYes5,767,251<disabled>Y
Organon Usa Inc
follitropin alfa/beta
INJECTABLE;SUBCUTANEOUS021211Feb 11, 2004DISCNNo5,767,251<disabled>Y
Organon Usa Inc
follitropin alfa/beta
INJECTABLE;SUBCUTANEOUS021211Mar 23, 2004RXYes5,767,251<disabled>Y
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International Patent Family for Patent: 5,767,251

Country Document Number Publication Date
Austria190461Apr 15, 2000
Austria169334Aug 15, 1998
Austria87317Apr 15, 1993
Austria79408Aug 15, 1992
Germany19675006Jun 12, 2008
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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