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Details for Patent: 5,645,815

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Patent 5,645,815 protects ACUTECT and is included in one NDA.

This patent has two hundred and forty-five patent family members in twenty-five countries.

This patent has expired prematurely due to non-payment of maintenance fees. See details below.

Summary for Patent: 5,645,815

Title: Radiolabled compounds for thrombus imaging
Abstract:This invention relates to radiolabeled scintigraphic imaging agents, and methods and reagents for producing such agents. Specifically, the invention relates to specific binding compounds, including peptides, that bind to a platelet receptor that is the platelet GPIIb/IIIa receptor, methods and kits for making such compounds, and methods for using such compounds labeled with technetium-99m via a covalently-linked radiolabel-binding moiety to image thrombi in a mammalian body.
Inventor(s): Dean; Richard T. (Bedford, NH), Lister-James; John (Bedford, NH), Civitello; Edgar R. (Bradford, NH)
Assignee: Diatide, Inc. (Londonderry, NH)
Application Number:08/439,905
Patent Claim Types:
see list of patent claims
Compound; Composition; Device; Use;
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Cis Bio Intl Sa
technetium tc-99m apcitide
INJECTABLE;INJECTION020887-001Sep 14, 1998DISCNNo5,645,815<disabled>
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Premature patent expiration for: 5,645,815

Expiration due to failure to pay maintenance fee

Patent Number Tradename Expiration Date
July 08, 2009

Non-Orange Book Patents for Patent: 5,645,815

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,007,792 Radiolabeled vasoactive intestinal peptides for diagnosis and therapy<disabled in preview>
6,183,722 Somatostatin analogs<disabled in preview>
6,214,316 Somatostatin analogs<disabled in preview>
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International Patent Family for Patent: 5,645,815

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Germany69531502Jun 24, 2004
Canada2124458Jan 30, 2001
South Africa9502206Dec 12, 1995
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.

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Copyright 2002-2016 thinkBiotech LLC
ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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