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Details for Patent: 5,637,611

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Summary for Patent: 5,637,611

Title: Medicaments
Abstract:Use of a compound of general formula (I): ##STR1## wherein: R.sup.1 represents hydrogen, halogen, trifluoromethyl, nitro, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, arylC.sub.1-6 alkoxy, --CO.sub.2 R.sup.4, --(CH.sub.2).sub.n CN, --(CH.sub.2).sub.n CONR.sup.5 R.sup.6, --(CH.sub.2).sub.n SO.sub.2 NR.sup.5 R.sup.6, C.sub.1-6 alkanoylamino (CH.sub.2).sub.n, or C.sub.1-6 alkylsulphonylamino (CH.sub.2).sub.n ; R.sup.4 represents hydrogen, C.sub.1-6 alkyl or arylC.sub.1-6 alkyl; R.sup.5 and R.sup.6 each independently represent hydrogen or C.sub.1-6 alkyl, or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are attached form a ring; n represents 0, 1 or 2; and R.sup.2 and R.sup.3 each independently represent hydrogen, C.sub.1-6 alkyl or benzyl or together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino or hexahydroazepino ring; or a physiologically acceptable salt thereof, in the manufacture of a medicament for the treatment of a condition where a 5-HT.sub.1 -like agonist is indicated, for example migraine. Novel compounds of formula (I), processes for preparing them and pharmaceutical compositions containing them are also described.
Inventor(s): King; Francis D. (Harlow, GB2), Gaster; Laramie M. (Harlow, GB2), Kaumann; Alberto J. (Trumpington, GB2), Young; Rodney C. (Hertford, GB2)
Assignee: SmithKline Beecham p.l.c. (GB2)
Application Number:08/442,719
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,637,611

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Slovakia131993Jun 08, 1994
Israel102322Sep 30, 1997
Portugal100620Jan 29, 1999
European Patent Office0591280Apr 13, 1994
Portugal100620Sep 30, 1993
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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