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Details for Patent: 5,629,327

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Summary for Patent: 5,629,327

Title: Methods and compositions for inhibition of angiogenesis
Abstract:The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
Inventor(s): D'Amato; Robert (Lancaster, PA)
Assignee: Childrens Hospital Medical Center Corp. (Boston, MA)
Application Number:08/168,817
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,629,327

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0688211Dec 27, 1995
New Zealand535670May 26, 2006
Germany69430796Jan 30, 2003
Brazil9400764Nov 01, 1994
Portugal688211Nov 29, 2002
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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