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|Title:||Dosage forms of risedronate|
|Abstract:||The present invention is directed to a novel enteric-coated oral dosage form of a risedronate active ingredient comprised of a safe and effective amount of a pharmaceutical composition which is comprised of a risedronate active ingredient and pharmaceutically-acceptable excipients. Said dosage forms prohibit the exposure of the risedronate active ingredient to the epithelial and mucosal tissues of the buccal cavity, pharynx, esophagus, and stomach and thereby protects said tissues from erosion, ulceration or other like irritation. Accordingly, the said dosage forms effect the delivery to the lower gastrointestinal tract of said human or other mammal of a safe and effective amount of the risedronate active ingredient, and substantially alleviate the esophagitis or esophageal irritation which occasionally accompanies the oral administration of risedronate active ingredients.|
|Inventor(s):||Dansereau; Richard J. (Sherburne, NY), Mosher; Russell Y. (Norwich, NY), Axelrod; Douglas W. (Norwich, NY), Sietsema; William K. (Norwich, NY)|
|Assignee:||The Procter & Gamble Company (Cincinnati, OH)|
Patent Claim Types:|
see list of patent claims
|Use; Composition; Dosage form; Delivery; Formulation;|
|Country||Document Number||Publication Date|
|World Intellectual Property Organization (WIPO)||9309785||May 27, 1993|
|United States of America||5935602||Aug 10, 1999|
|United States of America||6096342||Aug 01, 2000|
|United States of America||6596710||Jul 22, 2003|
|United States of America||2004037884||Feb 26, 2004|
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