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|Title:||GABA and L-glutamic acid analogs for antiseizure treatment|
|Abstract:||A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.|
|Inventor(s):||Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL), Yuen; Po-Wai (Ann Arbor, MI), Sobieray; Denis M. (Holland, MI), Franklin; Lloyd C. (Hamilton, MI), Schwindt; Mark A. (Holland, MI)|
|Assignee:||Northwestern University (Evanston, IL) Warner-Lambert Company (Ann Arbor, MI)|
Patent Claim Types:|
see list of patent claims
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|New Zealand||253459||Mar 24, 1997|
|World Intellectual Property Organization (WIPO)||9209560||Jun 11, 1992|
|Portugal||641330||Mar 28, 2002|
|European Patent Office||0641330||May 28, 1997||C00641330/01||Switzerland||<disabled>|
|European Patent Office||0641330||Oct 17, 2001||CA 2004 00036||Denmark||<disabled>|
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