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Details for Patent: 5,563,175

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Summary for Patent: 5,563,175

Title: GABA and L-glutamic acid analogs for antiseizure treatment
Abstract:A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
Inventor(s): Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL), Yuen; Po-Wai (Ann Arbor, MI), Sobieray; Denis M. (Holland, MI), Franklin; Lloyd C. (Hamilton, MI), Schwindt; Mark A. (Holland, MI)
Assignee: Northwestern University (Evanston, IL) Warner-Lambert Company (Ann Arbor, MI)
Application Number:08/420,575
Patent Claim Types:
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International Patent Family for Patent: 5,563,175

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0641330Mar 08, 1995C00641330/01Switzerland<disabled>
European Patent Office0641330May 28, 1997SPC016/2004Ireland<disabled>
Canada2134674Dec 21, 2004
European Patent Office0641330Oct 17, 2001SPC016/2004Ireland<disabled>
European Patent Office0641330May 28, 19972004C/022Belgium<disabled>
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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