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|Title:||GABA and L-glutamic acid analogs for antiseizure treatment|
|Abstract:||A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.|
|Inventor(s):||Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL), Yuen; Po-Wai (Ann Arbor, MI), Sobieray; Denis M. (Holland, MI), Franklin; Lloyd C. (Hamilton, MI), Schwindt; Mark A. (Holland, MI)|
|Assignee:||Northwestern University (Evanston, IL) Warner-Lambert Company (Ann Arbor, MI)|
Patent Claim Types:|
see list of patent claims
|Country||Document Number||Publication Date|
|Japan||4297814||Jul 15, 2009|
|Russian Federation||2140901||Nov 10, 1999|
|Czech Republic||286106||Jan 12, 2000|
|Germany||69330949||Nov 22, 2001|
|Japan||3856816||Dec 13, 2006|
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