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|Title:||Method of progesterone delivery and affect thereof|
|Abstract:||The present invention teaches that relatively low levels of serum progesterone, 1 to 6 ng/ml, may be used to prevent endometrial cancer. The vaginal delivery of progesterone using a cross-linked polycarboxylic polymer produces this low serum progesterone level while also providing the full secretory transformation of the endometrium, indicating the efficacy of the progesterone. Such low levels of serum progesterone will decrease the risk of breast cancer experienced by women undergoing hormone replacement therapy ("HRT") and minimize the potential of other undesirable progesterone associated side effects.|
|Inventor(s):||Bologna; William J. (New York, NY), Levine; Howard L. (Oceanside, NY)|
|Assignee:||Columbia Laboratories, Inc. (Coconut Grove, FL)|
Patent Claim Types:|
see list of patent claims
|Use; Delivery; Device;|
|Country||Document Number||Publication Date|
|South Africa||9407073||May 02, 1995|
|World Intellectual Property Organization (WIPO)||9507699||Mar 23, 1995|
|Russian Federation||2148393||May 10, 2000|
|Philippines||30813||Oct 17, 1997|
|New Zealand||273816||Sep 28, 2007|
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