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Details for Patent: 5,543,150

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Patent 5,543,150 protects CRINONE and is included in one NDA.

Summary for Patent: 5,543,150

Title: Method of progesterone delivery and affect thereof
Abstract:The present invention teaches that relatively low levels of serum progesterone, 1 to 6 ng/ml, may be used to prevent endometrial cancer. The vaginal delivery of progesterone using a cross-linked polycarboxylic polymer produces this low serum progesterone level while also providing the full secretory transformation of the endometrium, indicating the efficacy of the progesterone. Such low levels of serum progesterone will decrease the risk of breast cancer experienced by women undergoing hormone replacement therapy ("HRT") and minimize the potential of other undesirable progesterone associated side effects.
Inventor(s): Bologna; William J. (New York, NY), Levine; Howard L. (Oceanside, NY)
Assignee: Columbia Laboratories, Inc. (Coconut Grove, FL)
Application Number:08/122,371
Patent Claim Types:
see list of patent claims
Use; Delivery; Device;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Watson Labs
CRINONE
progesterone
GEL;VAGINAL020701Jul 31, 1997RXNo5,543,150<disabled>VAGINAL ADMINISTRATION OF PROGESTERONE USING SPECIFIED FORMULATION
Watson Labs
CRINONE
progesterone
GEL;VAGINAL020701Jul 31, 1997RXYes5,543,150<disabled>VAGINAL ADMINISTRATION OF PROGESTERONE USING SPECIFIED FORMULATION
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International Patent Family for Patent: 5,543,150

Country Document Number Publication Date
South Africa9407073May 02, 1995
World Intellectual Property Organization (WIPO)9507699Mar 23, 1995
Russian Federation2148393May 10, 2000
Philippines30813Oct 17, 1997
New Zealand273816Sep 28, 2007
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