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Details for Patent: 5,541,170

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Patent 5,541,170 protects DELZICOL, ASACOL, and ASACOL HD, and is included in three NDAs. There have been zero Paragraph IV challenges on Asacol HD and Asacol

Summary for Patent: 5,541,170

Title: Orally administrable pharmaceutical compositions
Abstract:A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below pH7 but soluble in colonic intestinal juice, in a sufficient amount that the oral dosage form remains intact until it reaches the colon. The preferred anionic polymer is a partly methyl esterified methacrylic acid polymer in which the ratio of free carboxylic groups to ester groups is about 1:2. The invention has particular application to dosage forms of prednisolone and salts thereof, indomethacin, ibuprofen, and, especially, 5-amino-salicylic acid.
Inventor(s): Rhodes; John (Cardiff, GB7), Evans; Brian K. (Dinas Powis, GB7)
Assignee: Tillotts Pharma AG (Ziefen, CH)
Application Number:08/401,696
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Dosage form;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Warner Chilcott Llc
DELZICOL
mesalamine
CAPSULE, DELAYED RELEASE;ORAL204412Feb 1, 2013RXYes5,541,170<disabled>YTREATMENT OF ULCERATIVE COLITIS
Warner Chilcott Llc
ASACOL
mesalamine
TABLET, DELAYED RELEASE;ORAL019651Jan 31, 1992RXYes5,541,170<disabled>TREATMENT OF ULCERATIVE COLITIS
Warner Chilcott Llc
ASACOL HD
mesalamine
TABLET, DELAYED RELEASE;ORAL021830May 29, 2008RXYes5,541,170<disabled>YTREATMENT OF ULCERATIVE COLITIS
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Foreign Priority and PCT Information for Patent: 5,541,170

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8123573Jul 31, 1981

International Patent Family for Patent: 5,541,170

Country Document Number Publication Date
South Africa8205384May 25, 1983
World Intellectual Property Organization (WIPO)8300435Feb 17, 1983
United States of America5541171Jul 30, 1996
Norway159696Oct 24, 1988
Norway830948Mar 17, 1983
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