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Details for Patent: 5,541,170

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Summary for Patent: 5,541,170

Title: Orally administrable pharmaceutical compositions
Abstract:A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below pH7 but soluble in colonic intestinal juice, in a sufficient amount that the oral dosage form remains intact until it reaches the colon. The preferred anionic polymer is a partly methyl esterified methacrylic acid polymer in which the ratio of free carboxylic groups to ester groups is about 1:2. The invention has particular application to dosage forms of prednisolone and salts thereof, indomethacin, ibuprofen, and, especially, 5-amino-salicylic acid.
Inventor(s): Rhodes; John (Cardiff, GB7), Evans; Brian K. (Dinas Powis, GB7)
Assignee: Tillotts Pharma AG (Ziefen, CH)
Application Number:08/401,696
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Dosage form;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,541,170

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8123573Jul 31, 1981

International Patent Family for Patent: 5,541,170

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0097651Jan 11, 1984
Denmark158931Aug 06, 1990
Finland85216Dec 13, 1991
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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