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Details for Patent: 5,538,739

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Summary for Patent: 5,538,739

Title: Sustained release formulations of water soluble peptides
Abstract:The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
Inventor(s): Bodmer; David (Klingnau, CH), Fong; Jones W. (Parsippany, NJ), Kissel; Thomas (Staufen, DE), Maulding, Jr.; Hawkins V. (Mendham, NJ), Nagele; Oskar (Sissach, CH), Pearson; Jane E. (Ogendensburg, NJ)
Assignee: Sandoz Ltd. (Basel, CH)
Application Number:07/643,880
Patent Claim Types:
see list of patent claims
Compound; Formulation;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Novartis
SANDOSTATIN LAR
octreotide acetate
INJECTABLE;INJECTION021008Nov 25, 1998RXNo5,538,739*PED<disabled>Y
Novartis
SANDOSTATIN LAR
octreotide acetate
INJECTABLE;INJECTION021008Nov 25, 1998RXYes5,538,739*PED<disabled>Y
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Foreign Priority and PCT Information for Patent: 5,538,739

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Hungary3974/90Jun 25, 1990
United Kingdom9016840Aug 01, 1990

International Patent Family for Patent: 5,538,739

Country Document Number Publication Date
South Africa9005327Mar 25, 1992
South Africa9106070Apr 28, 1993
United States of America5639480Jun 17, 1997
United States of America5688530Nov 18, 1997
United States of America5876761Mar 02, 1999
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