|Title:||Pharmaceutical compositions for oral use and method of preparing them|
|Abstract:||A pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) having antagonistic action to angiotensin II ##STR1## (wherein the ring W is an optionally substituted N-containing heterocyclic residue; R.sup.3 is a group capable of forming an anion or a group convertible thereinto; X is a direct bond or a spacer having an atomic length of two or less between the phenylene group and the phenyl group; and n is an integer of 1 or 2) and an oily substance having a lower melting point, and a method for preparing a pharmaceutical composition for oral use comprising an effective amount of a compound of the formula (I) and an oily substance having a lower melting point, which comprises admixing the compound of the formula (I) with an oily substance having a lower melting point and then subjecting the mixture to molding.|
|Inventor(s):||Makino; Tadashi (Osaka, JP), Mizukami; Yashio (Osaka, JP), Kikuta; Jun-ichi (Osaka, JP)|
|Assignee:||Takeda Chemical Industries, Ltd. (Osaka, JP)|
Patent Claim Types:|
see list of patent claims
|Composition; Compound; Dosage form; Use;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||3-304924||Nov 20, 1991|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|China||1047518||Dec 22, 1999|
|South Korea||100256633||May 15, 2000|
|Japan||H05194218||Aug 03, 1993|
|European Patent Office||0782852||Jul 09, 1997|
|Brazil||1100336||Apr 18, 2000|
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