|Title:||Crystals of N-(trans-4-isopropylcyclohexycarbonyl)-D-phenylalanine and methods for preparing them|
|Abstract:||Stable crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine may be produced by treating this compound with a solvent at a temperature of at least 10.degree. C. and forming crystals in the solvent at a temperature of at least 10.degree. C. For example, crystals may be formed by crystallization out of solution, or may be formed from solid particles of the compound suspended in a solvent. Crystals formed in this way have different melting point, infra red spectrum and X-ray diffraction patterns from previously known forms of the compound and have enhanced processability, eg. stability to grinding.|
|Inventor(s):||Sumikawa; Michito (Kawasaki, JP), Koguchi; Yoshihito (Kawasaki, JP), Ohgane; Takao (Kawasaki, JP), Irie; Yasuo (Kawasaki, JP), Takahashi; Satoji (Yottukaichi, JP)|
|Assignee:||Ajinomoto Co., Inc. (Tokyo, JP)|
Patent Claim Types:|
see list of patent claims
|Use; Formulation; Composition;|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|European Patent Office||0526171||May 05, 1993||SPC/GB01/047||United Kingdom||<disabled>|
|European Patent Office||0526171||May 05, 1993||C300063||Netherlands||<disabled>|
|European Patent Office||0526171||Mar 05, 1997||SPC/GB01/047||United Kingdom||<disabled>|
|Spain||2100291||Jun 16, 1997|
|Austria||149483||Mar 15, 1997|
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