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Details for Patent: 5,488,150

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Summary for Patent: 5,488,150

Title: Crystals of N-(trans-4-isopropylcyclohexycarbonyl)-D-phenylalanine and methods for preparing them
Abstract:Stable crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine may be produced by treating this compound with a solvent at a temperature of at least C. and forming crystals in the solvent at a temperature of at least C. For example, crystals may be formed by crystallization out of solution, or may be formed from solid particles of the compound suspended in a solvent. Crystals formed in this way have different melting point, infra red spectrum and X-ray diffraction patterns from previously known forms of the compound and have enhanced processability, eg. stability to grinding.
Inventor(s): Sumikawa; Michito (Kawasaki, JP), Koguchi; Yoshihito (Kawasaki, JP), Ohgane; Takao (Kawasaki, JP), Irie; Yasuo (Kawasaki, JP), Takahashi; Satoji (Yottukaichi, JP)
Assignee: Ajinomoto Co., Inc. (Tokyo, JP)
Application Number:08/166,144
Patent Claim Types:
see list of patent claims
Use; Formulation; Composition;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,488,150

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan3-189696Jul 30, 1991
Japan3-199453Aug 08, 1991

International Patent Family for Patent: 5,488,150

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0526171Feb 03, 1993C300063Netherlands<disabled>
Germany69217762Apr 10, 1997
Germany69217762Oct 09, 1997
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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