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|Title:||Pharmaceutical agents useful as leukotriene antagonists|
|Abstract:||The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.|
|Inventor(s):||Holohan; James J. (Macclesfield, GB2), Edwards; Ieuan J. (Congleton, GB2), Timko; Robert J. (West Chester, PA), Bradway; Randy J. (Downingtown, PA), Clements; Arlene (Turnersville, NJ)|
|Assignee:||Zeneca Limited (London, GB2)|
Patent Claim Types:|
see list of patent claims
|Composition; Compound; Dosage form; Use;|
|Country||Document Number||Publication Date|
|South Africa||9109771||Sep 30, 1992|
|United States of America||5319097||Jun 07, 1994|
|United States of America||5504216||Apr 02, 1996|
|United States of America||5612367||Mar 18, 1997|
|United States of America||5993859||Nov 30, 1999|
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