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Details for Patent: 5,474,979

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Summary for Patent: 5,474,979

Title: Nonirritating emulsions for sensitive tissue
Abstract:A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.
Inventor(s): Ding; Shulin (Irvine, CA), Tien; Walter L. (Irvine, CA), Olejnik; Orest (Trabuco Canyon, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:08/243,279
Patent Claim Types:
see list of patent claims
Composition; Use;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,474,979

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
South Korea100368181Apr 10, 2003
China1229136Nov 30, 2005
European Patent Office1044678Oct 18, 2000
China1198587Apr 27, 2005
Germany69522104Sep 13, 2001
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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