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|Title:||Nonirritating emulsions for sensitive tissue|
|Abstract:||A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.|
|Inventor(s):||Ding; Shulin (Irvine, CA), Tien; Walter L. (Irvine, CA), Olejnik; Orest (Trabuco Canyon, CA)|
|Assignee:||Allergan, Inc. (Irvine, CA)|
Patent Claim Types:|
see list of patent claims
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|World Intellectual Property Organization (WIPO)||9531211||Nov 23, 1995|
|New Zealand||287635||Sep 24, 1998|
|Spain||2161895||Dec 16, 2001|
|Japan||2003231646||Aug 19, 2003|
|European Patent Office||1044678||Oct 18, 2000|
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