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Last Updated: March 28, 2024

Details for Patent: 5,463,116


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Summary for Patent: 5,463,116
Title: Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
Abstract:Stable crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine may be produced by treating this compound with a solvent at a temperature of at least 10.degree. C. and forming crystals in the solvent at a temperature of at least 10.degree. C. For example, crystals may be formed by crystallization out of solution, or may be formed from solid particles of the compound suspended in a solvent. Crystals formed in this way have different melting point, infra red spectrum and X-ray diffraction patterns from previously known forms of the compound and have enhanced processability, e.g., stability to grinding.
Inventor(s): Sumikawa; Michito (Kawasaki, JP), Koguchi; Yoshihito (Kawasaki, JP), Ohgane; Takao (Kawasaki, JP), Irie; Yasuo (Kawasaki, JP), Takahashi; Satoji (Yottukaichi, JP)
Assignee: Ajinomoto Co., Inc. (Tokyo, JP)
Application Number:08/190,460
Patent Claim Types:
see list of patent claims
Compound; Composition; Use; Formulation;

Drugs Protected by US Patent 5,463,116

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,463,116

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan3-189696Jul 30, 1991
Japan3-199453Aug 08, 1991

International Family Members for US Patent 5,463,116

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 149483 ⤷  Try a Trial
Brazil 1100807 ⤷  Try a Trial
Canada 2114678 ⤷  Try a Trial
Germany 10199058 ⤷  Try a Trial
Germany 69217762 ⤷  Try a Trial
Denmark 0526171 ⤷  Try a Trial
European Patent Office 0526171 ⤷  Try a Trial SPC/GB01/047 United Kingdom ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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