Details for Patent: 5,453,510
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Summary for Patent: 5,453,510
Title: | Neuromuscular blocking agents |
Abstract: | 1R-cis,1'R-cis isomer of a 2',2'-(3,11-dioxo-4,10-dioxatridecylene)-bis(1,2,3,4-tetrahydro-6, 7-dimethoxy-2-methyl-1-veratrylisoquinolium) said, substantially free from other geometrical and optical isomers thereof. The 1R-cis,1'R-cis isomer has been found to have an advantageous combination of pharmacological properties, notably greater neuromuscular blocking potency, weaker histamine-releasing potency, and at equivalent levels of neuromuscular blockade, fewer potential adverse effects on the autonomic nervous system (sympathetic and parasympathetic blockage), in comparison with the known mixture of geometrical and optical isomers. |
Inventor(s): | Hill; Derek A. (Dartford, GB2), Turner; Geoffrey L. (Dartford, GB2) |
Assignee: | Burroughs Wellcome Co. (Research Triangle Park, NC) |
Application Number: | 07/911,887 |
Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 5,453,510
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,453,510
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
United Kingdom | 9015473 | Jul 13, 1990 |
International Family Members for US Patent 5,453,510
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 138369 | ⤷ Try a Trial | |||
Australia | 1134695 | ⤷ Try a Trial | |||
Australia | 687481 | ⤷ Try a Trial | |||
Australia | 8190491 | ⤷ Try a Trial | |||
Belgium | 1003407 | ⤷ Try a Trial | |||
Canada | 2087104 | ⤷ Try a Trial | |||
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