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Details for Patent: 5,447,926

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Patent 5,447,926 protects BESIVANCE and is included in one NDA.

Summary for Patent: 5,447,926

Title: Quinolone carboxylic acid derivatives
Abstract:A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R.sup.1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R.sup.2 is a hydrogen atom or an amino group which may be substituted by one or two lower alkyl groups, X is a hydrogen atom or a halogen atom, Y is CH.sub.2, O, S, SO, SO.sub.2, or N--R.sup.3, wherein R.sup.3 is a hydrogen atom or a lower alkyl group, and Z is an oxygen atom or two hydrogen atoms; or a salt thereof; and an antimicrobial agent comprising the same. The compound exhibits a superior antimicrobial activity, especially against gram positive microorganisms, and is thus useful for the treatments and prevention of various infectious diseases in clinics.
Inventor(s): Konno; Fujiko (Tomisato, JP), Shibata; Akihiro (Yachiyo, JP), Matsuda; Hideaki (Abiko, JP), Asaoka; Takemitsu (Narita, JP), Kawahara; Ryuichi (Ichikawa, JP), Taido; Naokata (Funabashi, JP), Kuraishi; Tasdayuki (Chiba, JP), Takeda; Sunao (Ichihara, JP)
Assignee: SS Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:08/305,977
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Bausch And Lomb
besifloxacin hydrochloride
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Foreign Priority and PCT Information for Patent: 5,447,926

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2-191339Jul 19, 1990
Japan3-079774Apr 12, 1991

International Patent Family for Patent: 5,447,926

Country Document Number Publication Date
World Intellectual Property Organization (WIPO)9201676Feb 06, 1992
United States of America5385900Jan 31, 1995
Japan5004968Jan 14, 1993
Japan2613139May 21, 1997
Japan8169880Jul 02, 1996
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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