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Details for Patent: 5,439,686

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Summary for Patent: 5,439,686

Title: Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
Abstract:In accordance with the present invention, there are provided compositions for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug taxol) in which the pharmacologically active agent is delivered in a soluble form or in the form of suspended particles. In particular, the soluble form may comprise a solution of pharmacologically active agent in a biocompatible dispersing agent contained within a protein walled shell. Alternatively, the protein walled shell may contain particles of taxol. In another aspect, the suspended form comprises particles of pharmacologically active agent in a biocompatible aqueous liquid.
Inventor(s): Desai; Neil P. (Los Angeles, CA), Soon-Shiong; Patrick (Los Angeles, CA), Sandford; Paul A. (Los Angeles, CA), Grinstaff; Mark W. (Pasadena, CA), Suslick; Kenneth S. (Champaign, IL)
Assignee: VivoRx Pharmaceuticals, Inc. (Santa Monica, CA)
Application Number:08/023,698
Patent Claim Types:
see list of patent claims
Composition; Delivery; Formulation; Use;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,439,686

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Canada2446083Jan 06, 2015
Hong Kong1024866Nov 13, 2009
European Patent Office1337249Aug 27, 2003
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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