|Title:||Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor|
|Abstract:||In accordance with the present invention, there are provided compositions for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug taxol) in which the pharmacologically active agent is delivered in a soluble form or in the form of suspended particles. In particular, the soluble form may comprise a solution of pharmacologically active agent in a biocompatible dispersing agent contained within a protein walled shell. Alternatively, the protein walled shell may contain particles of taxol. In another aspect, the suspended form comprises particles of pharmacologically active agent in a biocompatible aqueous liquid.|
|Inventor(s):||Desai; Neil P. (Los Angeles, CA), Soon-Shiong; Patrick (Los Angeles, CA), Sandford; Paul A. (Los Angeles, CA), Grinstaff; Mark W. (Pasadena, CA), Suslick; Kenneth S. (Champaign, IL)|
|Assignee:||VivoRx Pharmaceuticals, Inc. (Santa Monica, CA)|
Patent Claim Types:|
see list of patent claims
|Composition; Delivery; Formulation; Use;|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Israel||133672||Sep 01, 2009|
|South Korea||20070091051||Sep 06, 2007|
|South Korea||100904931||Jun 29, 2009|
|Japan||3746293||Feb 15, 2006|
|New Zealand||525580||Aug 27, 2004|
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