Patent 5,435,076 protects and is included in zero NDA.
|Abstract:||A device for an injection apparatus, including a dual-chamber injection cartridge. The cartridge includes a front end, a rear end, a front opening in the vicinity of a front end of the cartridge, a front chamber located in the vicinity of the front opening and including a drug freeze-dried in the front chamber, a rear chamber including a liquid component, a movable wall separating the front chamber and the rear chamber, a bypass for transferring the liquid component between the front chamber and the rear chamber, and a rear piston. The cartridge is slidably arranged within a cylindrical sleeve substantially the same length as the cartridge. A stopper is located in the vicinity of the front opening of the cartridge. The stopper is directed rearwardly coaxially with the cartridge, wherein as the sleeve is displaced rearwardly after the freeze-drying of the drug, the stopper enters the front opening of the cartridge to sealingly close the cartridge. An actuator for actuating the rear piston may be attached in the vicinity of the rear end of the cartridge.|
|Inventor(s):||Hjertman; Birger (Vallingby, SE), Levander; Gustav (Bromma, SE), Ljungquist; Olle (Taby, SE)|
|Assignee:||Pharmacia Aktiebolag (SE)|
Patent Claim Types:|
see list of patent claims
|Device; Process; Formulation;|
|Country||Document Number||Publication Date|
|World Intellectual Property Organization (WIPO)||9320869||Oct 28, 1993|
|Sweden||9201247||Apr 21, 1992|
|New Zealand||252761||Mar 26, 1996|
|Japan||H06508543||Sep 29, 1994|
|Japan||2726906||Mar 11, 1998|
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