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Details for Patent: 5,403,833

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Summary for Patent: 5,403,833

Title: Methods of inhibiting transplant rejecton in mammals using rapamycin and derivatives and prodrugs thereof
Abstract:This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
Inventor(s): Calne; Sir Roy (Cambridge, GB2)
Application Number:08/192,648
Patent Claim Types:
see list of patent claims
Use; Delivery;
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International Patent Family for Patent: 5,403,833

Country Document Number Publication Date
Austria135215Mar 15, 1996
Australia5686590Jan 31, 1991
Australia638253Jun 24, 1993
Canada2018287Dec 06, 1990
Germany69025803Apr 18, 1996
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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