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Details for Patent: 5,284,858

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Patent 5,284,858 protects AMITIZA and is included in one NDA. There has been one Paragraph IV challenge on Amitiza.

This patent has ten patent family members in eight countries.

Summary for Patent: 5,284,858

Title: Prostaglandins E and anti ulcers containing same
Abstract:The novel 13, 14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-ketoprostaglandins E of the invention have an advatage that they have none of side effects which prostaglandin E intrinsically has, or can remarakably reduce such effects of the prostaglandin E. Therefore, the novel 13, 14-dihydro-15-keto prostaglandins E of the invention are effective for animal and human use for treatment and prevention of ulcers, such as duodenal ulcer and gastric ulcer.
Inventor(s): Ueno; Ryuzo (Nishinomiya, JP), Ueno; Ryuji (Kyoto, JP), Kato; Ichie (Kawanishi, JP), Oda; Tomio (Itami, JP)
Assignee: Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (Osaka, JP)
Application Number:07/925,220
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Sucampo Pharma Llc
CAPSULE;ORAL021908-002Apr 29, 2008RXNo5,284,858<disabled>Y
Sucampo Pharma Llc
CAPSULE;ORAL021908-001Jan 31, 2006RXYes5,284,858<disabled>Y
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Foreign Priority and PCT Information for Patent: 5,284,858

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan62-18820Jan 28, 1987
Japan62-65352Mar 18, 1987

International Patent Family for Patent: 5,284,858

Country Document Number Publication Date
United States of America5428062Jun 27, 1995
United States of America5380709Jan 10, 1995
United States of America5225439Jul 06, 1993
United States of America6265440Jul 24, 2001
Spain2043798Jan 01, 1994
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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